Festival organisers have chosen to host the European premiere of the Dickens classic directed by Mike Newell.
Newell, who previously directed Four Weddings and a Funeral, said: "I'm proud that our new version of Great Expectations should be presented this year, the bi-centenary of Dickens' birth.
"I've tried to make a film that is true to the theatrical vividness, energetic characters and high colour that he is loved for, while mining the deep seams of emotional cruelty and madness that underlie one of Dickens' darkest-shadowed stories.
"I've tried to make a film for a young modern audience in which Pip and Estella's fated love affair is shown through feelings and stresses that are of today and in a city that was, then, full of brawling energy, was unimaginably wealthy and very bad."
The story of orphan pip and his mysterious benefactor was most famously brought to life in 1946 by David Lean, but the new version has been highly anticipated with appearances from Helena Bonham Carter, David Walliams and Ralph Fiennes.
The cast also includes Robbie Coltrane, Ewen Bremner and Tamzin Outhwaite.
The event, formally known as the 56th BFI London Film Festival, will open with the European premiere of Tim Burton's Frankenweenie.